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“…[I]nterest in shark cartilage as an anticancer agent arose because many people believed that sharks did no longer get most cancers.” Why would they suppose one of these component?

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Because a few shark-cartilage supplement hawker wrote a e-book known as Sharks Don’t Get Cancer. But that’s certainly now not real.

“Sharks do get cancer.” “…[B]oth benign and cancerous…lesions have been pronounced in 21 species of sharks from [more than] 9 households.” For instance, this oral tumor spilling out of the mouth of this first-rate white.

Now, a few “shark cartilage vendors insist [instead] that sharks [just] rarely get cancer,” [but] actual most cancers shares in sharks have [never] been decided.” “[T]right here [has simply] been no systematic tumor surveys of sharks” for them to make one of these claim. But look, “even supposing sharks [were] less prone to cancer,” how can one logically bounce from that to cancer patients benefiting from ingesting powdered cartilage from a shark?

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“We realize, for example, that there are [certain] proteins that permit [some bacteria to survive] within boiling hot [springs].” Uh, does that mean if we eat those bacteria we will survive boiling water, too?

It doesn’t make any feel. “The illogic at the back of the pursuit of shark cartilage cures has implications beyond the reduction of shark populations and the misdirection of patients to ineffective most cancers treatment plans.” The stuff can be harmful, and i’m no longer simply speakme about the uncommon case of “shark cartilage-induced liver [inflammation].” Shark products can include the neurotoxin BMAA, which I’ve mentioned earlier than.

It’s been detected at multiplied degrees inside the brains of Alzheimer’s ailment and ALS patients, and can “play…a position within [the development of] neurodegenerative illnesses.” So, the “intake of shark-fin soup may additionally pose a extensive health threat.” But what about shark-cartilage dietary supplements?

They tested 16 business shark-cartilage supplements, right off the cabinets, and observed BMAA “in fifteen out of sixteen.” But look, although shark-cartilage dietary supplements convey “pro-inflammatory properties, which could pose a ability health risk for consumers,” we’re speaking about most cancers.

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There are chemotherapy agents which might be existence-threateningly dangerous, however now and again the advantages can outweigh the risks, while confronted with most cancers.

So, the query then becomes:

are there any benefits to shark cartilage? I mean, it’s now not a very wacky idea.

“[C]artilage [in general] is exceedingly immune to invasion through tumor cells.” So, maybe there’s a few “cartilage-derived anti-invasion thing.” “Less exciting alternative causes…are” that it’s simply hard for the cancer to penetrate the cartilage, or possibly because of the terrible blood supply in cartilage, cancer doesn’t do not forget it in particular fertile floor.

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But maybe that loss of blood vessels in cartilage may be exploited. The motive that no blood vessels come to be within cartilage is because cartilage cells provide angiogenesis inhibitors, blood vessel-introduction inhibitors.

So, maybe we can starve tumor increase by way of infusing those cartilage factors.

What scientists do is implant tumors into the eyeballs of rabbits, in an effort to visualize what number of blood vessels the tumor is capable of draw to itself. And, indeed:

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“Shark cartilage includes inhibitors of tumor angiogenesis.” “Such findings made the sales [of shark cartilage sky]rocket, [driving]…two shark species…to the edge of extinction.” But, cow cartilage does the equal issue.

Here, they used bovine cartilage. And so does human cartilage, for that depend.

So, why promote shark cartilage?

Well, it does sound so much more extraordinary, and sharks have like 10 times extra cartilage per animal.

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One 20-foot shark may want to net like 50 kilos of cartilage.

Just due to the fact cartilage has blood vessel-inhibiting chemical compounds within it, though, doesn’t imply if cancer sufferers devour it, it'll assist them.

It’s type of like magical questioning: shark cartilage stops blood-vessel increase.

“Thus, with the aid of ingesting shark cartilage, human beings will [somehow] be…blanketed.” I suggest, the “shark cartilage protein molecules [would seem to be] too large to be absorbed with the aid of the intestine.” It’s now not such as you’re injecting shark cartilage into your bloodstream thru an IV.

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But there has been this rat poll that did find that simply feeding shark cartilage to the animals, you may cut down on blood vessel growth within their bodies.

Okay, But Does That Translate Out To Stopping The Growth And Spread Of Cancer?

Apparently no longer, as “none of the shark cartilage doses examined had any retarding impact on [cancer growth]” or spread within tumor-bearing mice.

But just because it doesn’t work within rodents doesn’t suggest it doesn’t work in humans.