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Where Did That Even Come From?

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In the 80s, a crew of respected Norwegian researchers reported a weird finding. They had been evaluating the urine of autistic youngsters to the urine of everyday children, within desire of teasing out any differences that could cause hints as to what the purpose is.

This is a urine profile, which suggests spikes for every of the various components.

This is what everyday urine comes out like, with the peptides vicinity quite quiet. (Peptides are like small pieces of proteins, and commonly, we shouldn’t be peeing out a whole lot protein).

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But this is the urine profile from a baby with autism, with all varieties of peptide spikes.

Here’s some other one. This raised the query:

“Can the Pathophysiology [the dysfunction] of Autism be Explained by way of the Nature of the[se] Discovered Urine Peptides?” First, they needed to response:

“Where do the peptides come from?” They didn’t understand.

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But, there has been a clue:

most of the dad and mom of autistic children suggested that they were given worse once they were uncovered to cow’s milk.

Huh? Well, there are those proteins:

gluten, a protein within wheat, and casein, a protein in milk, that ruin down now not most effective into peptides, but exorphins.

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Exorphins are “opioid peptides derived from food proteins”—”known as exorphins…because of their exogenous starting place [meaning from outside of the body] and morphine-like interest,” in preference to endorphins, which might be morphine-like compounds we offer interior our our bodies. So, maybe some of those food peptides constitute like “A New Class of Hormones?” So, is that what the children have been peeing out?

Apparently so, as some of the ones peptides had opioid activity.

Okay. So, maybe they have been onto something.

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There are “[t]wo types of opioids [that] had been found within milk.” One is the “casomorphins in view in their morphine-like interest and their starting place.” They are breakdown products, fragments of the milk protein casein.

What’s the other one? The different opioid is the actual opiate:

morphine.

There seems to be actual morphine within milk.

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This can’t just be a coincidence.

“It is [hard] to accept as true with that those, or other sorts of opioids determined in the milk, are with out physiological or nutritional significance.” And, consider it;

it makes total sense. “Morphine and the opioid peptides can also…have an vital role inside the mom-toddler bond…” We need infants to be “’addicted’ to their very own mother’s milk.” Okay.

But, what approximately the milk of any other species?

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“Human [breast] milk is markedly specific from that of other…species [in that it] has the lowest” casein content, and human casein is a markedly one of a kind protein in phrases of its sequence of amino acid constructing blocks. Human milk has 15 instances less casein than bovine milk, and differs series-clever through about 1/2, and so breaks down into peptides otherwise.

Twenty-one bioactive peptides had been recovered from cow casein, including a couple of casomorphins, as compared to most effective five active peptides recognized in human milk, and best one casomorphin.

And, the casomorphins “from bovine casein are stronger.” This is a picture of opioid hobby, in which lower way more potent. Here’s the potency of straight morphine.

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