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“…[I]nterest in shark cartilage as an anticancer agent arose due to the fact many people believed that sharks did not get most cancers.” Why would they assume this kind of factor?

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Because some shark-cartilage supplement hawker wrote a e book referred to as Sharks Don’t Get Cancer. But that’s virtually now not real.

“Sharks do get cancer.” “…[B]oth benign and cancerous…lesions had been mentioned within 21 species of sharks from [more than] 9 families.” For example, this oral tumor spilling out of the mouth of this remarkable white.

Now, some “shark cartilage vendors insist [instead] that sharks [just] rarely get cancer,” [but] actual cancer shares within sharks have [never] been decided.” “[T]right here [has simply] been no systematic tumor surveys of sharks” for them to make this kind of declare. But appearance, “even supposing sharks [were] less vulnerable to most cancers,” how can one logically soar from that to most cancers sufferers taking advantage of ingesting powdered cartilage from a shark?

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“We understand, as an instance, that there are [certain] proteins that allow [some bacteria to survive] in boiling hot [springs].” Uh, does that suggest if we eat the ones micro organism we will continue to exist boiling water, too?

It doesn’t make any experience. “The illogic behind the pursuit of shark cartilage therapies has implications beyond the discount of shark populations and the misdirection of patients to ineffective most cancers treatment plans.” The stuff can be dangerous, and i’m no longer just speaking approximately the uncommon case of “shark cartilage-brought about liver [inflammation].” Shark products can comprise the neurotoxin BMAA, which I’ve talked about before.

It’s been detected at improved tiers in the brains of Alzheimer’s disorder and ALS patients, and might “play…a function in [the development of] neurodegenerative sicknesses.” So, the “intake of shark-fin soup might also pose a full-size fitness risk.” But what approximately shark-cartilage dietary supplements?

They examined 16 industrial shark-cartilage dietary supplements, proper off the shelves, and observed BMAA “in fifteen out of sixteen.” But appearance, although shark-cartilage dietary supplements deliver “seasoned-inflammatory properties, that could pose a potential fitness danger for purchasers,” we’re talking approximately cancer.

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There are chemotherapy agents that are lifestyles-threateningly dangerous, however sometimes the benefits can outweigh the risks, whilst faced with cancer.

So, the query then turns into:

are there any blessings to shark cartilage? I imply, it’s now not a completely wacky concept.

“[C]artilage [in general] is rather proof against invasion with the aid of tumor cells.” So, maybe there’s a few “cartilage-derived anti-invasion thing.” “Less thrilling opportunity reasons…are” that it’s simply difficult for the most cancers to penetrate the cartilage, or possibly because of the negative blood deliver within cartilage, cancer doesn’t keep in mind it especially fertile ground.

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But maybe that loss of blood vessels in cartilage can be exploited. The cause that no blood vessels grow to be in cartilage is because cartilage cells produce angiogenesis inhibitors, blood vessel-introduction inhibitors.

So, perhaps we will starve tumor increase through infusing these cartilage elements.

What scientists do is implant tumors into the eyeballs of rabbits, to be able to visualize how many blood vessels the tumor is capable of draw to itself. And, indeed:

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“Shark cartilage carries inhibitors of tumor angiogenesis.” “Such findings made the sales [of shark cartilage sky]rocket, [driving]… shark species…to the threshold of extinction.” But, cow cartilage does the identical aspect.

Here, they used bovine cartilage. And so does human cartilage, for that rely.

So, why promote shark cartilage?

Well, it does sound so much extra unique, and sharks have like 10 instances more cartilage consistent with animal.

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One 20-foot shark could net like 50 kilos of cartilage.

Just due to the fact cartilage has blood vessel-inhibiting chemicals in it, though, doesn’t suggest if cancer patients devour it, it'll help them.

It’s form of like magical questioning: shark cartilage stops blood-vessel boom.

“Thus, through consuming shark cartilage, human beings will [somehow] be…blanketed.” I suggest, the “shark cartilage protein molecules [would seem to be] too massive to be absorbed with the aid of the intestine.” It’s not such as you’re injecting shark cartilage into your bloodstream thru an IV.

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But there was this rat study that did discover that simply feeding shark cartilage to the animals, you could reduce down on blood vessel boom through their bodies.

Okay, But Does That Translate Out To Stopping The Growth And Spread Of Cancer?

Apparently not, as “not one of the shark cartilage doses examined had any retarding impact on [cancer growth]” or unfold in tumor-bearing mice.

But simply as it doesn’t paintings within rodents doesn’t mean it doesn’t work in people.